Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Bmp2  bone morphogenetic protein 2   (Synonyms: Bmp2a)
Results	Reference
1*	J:184022 Aizawa R, Yamada A, Suzuki D, Iimura T, Kassai H, Harada T, Tsukasaki M, Yamamoto G, Tachikawa T, Nakao K, Yamamoto M, Yamaguchi A, Aiba A, Kamijo R, Cdc42 is required for chondrogenesis and interdigital programmed cell death during limb development. Mech Dev. 2012 Mar;129(1-4):38-50
1*	J:75699 Albrecht AN, Schwabe GC, Stricker S, Boddrich A, Wanker EE, Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67
1	J:117635 Bose K, Nischt R, Page A, Bader BL, Paulsson M, Smyth N, Loss of nidogen-1 and -2 results in syndactyly and changes in limb development. J Biol Chem. 2006 Dec 22;281(51):39620-9
1*	J:183829 Correa SM, Washburn LL, Kahlon RS, Musson MC, Bouma GJ, Eicher EM, Albrecht KH, Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway. PLoS Genet. 2012 Apr;8(4):e1002569
1*	J:150879 Dathe K, Kjaer KW, Brehm A, Meinecke P, Nurnberg P, Neto JC, Brunoni D, Tommerup N, Ott CE, Klopocki E, Seemann P, Mundlos S, Duplications involving a conserved regulatory element downstream of BMP2 are associated with brachydactyly type A2. Am J Hum Genet. 2009 Apr;84(4):483-92
1*	J:54066 Dupe V, Ghyselinck NB, Thomazy V, Nagy L, Davies PJA, Chambon P, Mark M, Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods. Dev Biol. 1999 Apr 1;208(1):30-43
1	J:218159 Eshkar-Oren I, Krief S, Ferrara N, Elliott AM, Zelzer E, Vascular patterning regulates interdigital cell death by a ROS-mediated mechanism. Development. 2015 Feb 15;142(4):672-80
1	J:152865 Georgas K, Rumballe B, Valerius MT, Chiu HS, Thiagarajan RD, Lesieur E, Aronow BJ, Brunskill EW, Combes AN, Tang D, Taylor D, Grimmond SM, Potter SS, McMahon AP, Little MH, Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Dev Biol. 2009 Aug 15;332(2):273-86
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:276702 Hildebrand L, Schmidt-von Kegler M, Walther M, Seemann P, Stange K, Limb specific Acvr1-knockout during embryogenesis in mice exhibits great toe malformation as seen in Fibrodysplasia Ossificans Progressiva (FOP). Dev Dyn. 2019 May;248(5):396-403
1	J:46930 Jiang R, Lan Y, Chapman HD, Shawber C, Norton CR, Serreze DV, Weinmaster G, Gridley T, Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. Genes Dev. 1998 Apr 1;12(7):1046-57
1*	J:54206 Jung HS, Oropeza V, Thesleff I, Shh, Bmp-2, Bmp-4 and Fgf-8 are associated with initiation and patterning of mouse tongue papillae. Mech Dev. 1999 Mar;81(1-2):179-82
1	J:231462 Kaltcheva MM, Anderson MJ, Harfe BD, Lewandoski M, BMPs are direct triggers of interdigital programmed cell death. Dev Biol. 2016 Mar 15;411(2):266-76
1	J:198828 Kelly CE, Thymiakou E, Dixon JE, Tanaka S, Godwin J, Episkopou V, Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension. PLoS Biol. 2013;11(4):e1001538
1	J:56749 Keranen SV, Kettunen P, Aberg T, Thesleff I, Jernvall J, Gene expression patterns associated with suppression of odontogenesis in mouse and vole diastema regions. Dev Genes Evol. 1999 Aug;209(8):495-506
1	J:130369 Koo BK, Yoon MJ, Yoon KJ, Im SK, Kim YY, Kim CH, Suh PG, Jan YN, Kong YY, An obligatory role of mind bomb-1 in notch signaling of Mammalian development. PLoS One. 2007;2(11):e1221
1	J:98917 Lallemand Y, Nicola MA, Ramos C, Bach A, Cloment CS, Robert B, Analysis of Msx1; Msx2 double mutants reveals multiple roles for Msx genes in limb development. Development. 2005 Jul;132(13):3003-14
1	J:173657 Lavery R, Lardenois A, Ranc-Jianmotamedi F, Pauper E, Gregoire EP, Vigier C, Moreilhon C, Primig M, Chaboissier MC, XY Sox9 embryonic loss-of-function mouse mutants show complete sex reversal and produce partially fertile XY oocytes. Dev Biol. 2011 Jun 1;354(1):111-22
1*	J:146434 Maatouk DM, Choi KS, Bouldin CM, Harfe BD, In the limb AER Bmp2 and Bmp4 are required for dorsal-ventral patterning and interdigital cell death but not limb outgrowth. Dev Biol. 2009 Mar 15;327(2):516-23
1	J:143586 Manuylov NL, Smagulova FO, Leach L, Tevosian SG, Ovarian development in mice requires the GATA4-FOG2 transcription complex. Development. 2008 Nov;135(22):3731-43
1	J:155754 McCulloch DR, Nelson CM, Dixon LJ, Silver DL, Wylie JD, Lindner V, Sasaki T, Cooley MA, Argraves WS, Apte SS, ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression. Dev Cell. 2009 Nov;17(5):687-98
1	J:262487 Murgai A, Altmeyer S, Wiegand S, Tylzanowski P, Stricker S, Cooperation of BMP and IHH signaling in interdigital cell fate determination. PLoS One. 2018;13(5):e0197535
1*	J:169180 Okada I, Hamanoue H, Terada K, Tohma T, Megarbane A, Chouery E, Abou-Ghoch J, Jalkh N, Cogulu O, Ozkinay F, Horie K, Takeda J, Furuichi T, Ikegawa S, Nishiyama K, Miyatake S, Nishimura A, Mizuguchi T, Niikawa N, Hirahara F, Kaname T, Yoshiura K, Tsurusaki Y, Doi H, Miyake N, Furukawa T, Matsumoto N, Saitsu H, SMOC1 is essential for ocular and limb development in humans and mice. Am J Hum Genet. 2011 Jan 7;88(1):30-41
1*	J:77812 Perriton CL, Powles N, Chiang C, Maconochie MK, Cohn MJ, Sonic hedgehog signaling from the urethral epithelium controls external genital development. Dev Biol. 2002 Jul 1;247(1):26-46
1*	J:35807 Phippard DJ, Weber-Hall SJ, Sharpe PT, Naylor MS, Jayatalake H, Maas R, Woo I, Roberts-Clark D, Francis-West PH, Liu YH, Maxson R, Hill RE, Dale TC, Regulation of Msx-1, Msx-2, Bmp-2 and Bmp-4 during foetal and postnatal mammary gland development. Development. 1996 Sep;122(9):2729-37
1	J:154460 Suzuki D, Yamada A, Amano T, Yasuhara R, Kimura A, Sakahara M, Tsumaki N, Takeda S, Tamura M, Nakamura M, Wada N, Nohno T, Shiroishi T, Aiba A, Kamijo R, Essential mesenchymal role of small GTPase Rac1 in interdigital programmed cell death during limb development. Dev Biol. 2009 Nov 15;335(2):396-406
1*	J:157085 Villacorte M, Suzuki K, Hayashi K, de Sousa Lopes SC, Haraguchi R, Taketo MM, Nakagata N, Yamada G, Antagonistic crosstalk of Wnt/beta-catenin/Bmp signaling within the Apical Ectodermal Ridge (AER) regulates interdigit formation. Biochem Biophys Res Commun. 2010 Jan 22;391(4):1653-7
1*	J:60837 Zhang Y, Zhang Z, Zhao X, Yu X, Hu Y, Geronimo B, Fromm SH, Chen YP, A new function of BMP4: dual role for BMP4 in regulation of Sonic hedgehog expression in the mouse tooth germ. Development. 2000 Apr;127(7):1431-43
1*	J:139188 Zhao H, Oka K, Bringas P, Kaartinen V, Chai Y, TGF-beta type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner. Dev Biol. 2008 Aug 1;320(1):19-29
1	J:156950 Zhao X, Brade T, Cunningham TJ, Duester G, Retinoic acid controls expression of tissue remodeling genes Hmgn1 and Fgf18 at the digit-interdigit junction. Dev Dyn. 2010 Feb;239(2):665-71